Product ID:TEMOVATE R GEL
MSDS Date:12/19/1994
FSC:6505
NIIN:00F041350
MSDS Number: BXNNW

GLAXO INC

5 MOORE DR
RESEARCH TRIANGLE PARK, NC 27709-5000
US

Emergency Phone: 919-248-2100/919-248-2700

Info Phone: 919-248-2100/919-248-2700

Cage: 34006

GLAXO WELLCOME INC.

13398 DURHAM, NC 27709 US

Telephone: 919-248-2100

Cage: 34006

1,2-PROPANEDIOL (PROPYLENE GLYCOL)

CAS: 57-55-6

RTECS: TY2000000

Fraction By Weight: 65%

CLOBETASOL PROPIONATE *95-2*

CAS: 25122-46-7

RTECS: TU3725000

Fraction By Weight: 0.05%

Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:SKIN: MAY RESULT IN ABSORPTION,
IRRITATION & DERMATITIS. SYSTEMIC EFFECTS OF TEMOVATE GEL COULD
INCLUDE SUPPRESSION OF THE ADRENAL CORTEX, WHICH RESULTS IN
DECREASED ABILITY TO RESPOND TO STRESS, SERI OUS ILLNESS, SURGERY &
INFECTIONS. DEPRESSED ADRENAL FUNCTION MAY ALSO RESULT IN DIABETES.
EYES: IRRITATION.
Explanation of Carcinogenicity:NONE
Effects of Overexposure:ITCHING, BURNING, IRRITATION, DRYNESS, REDNESS,
HIGH BLOOD SUGAR, SUGAR IN THE URINE, FLUID & SALT RETENTION,
SWELLING, ABNORMAL FAT DEPOSITION, WEIGHT GAIN, INCREASED APPETITE,
CATARACT DEVELOPMENT, BRUISING.
Medical Cond Aggravated by Exposure:HYPERSENSITIVE TO CORTICOSTEROIDS.

First Aid:EYES: FLUSH W/LARGE AMOUNTS OF COOL WATER FOR 15 MINS. SKIN:
WASH AREAS W/SOAP & WATER. INHALATION: IF NOT BREATHING, GIVE CPR.
IF BREATHING IS DIFFICULT, GIVE OXYGEN IF NEEDED. INGESTION: RINSE
MOUTH W/WATER. NEVER GIVE ANYTHING BY MOUTH IF UNCONSCIOUS/HAVING
CONVULSIONS. OBTAIN MEDICAL ATTENTION IN ALL CASES.

Extinguishing Media:WATER SPRAY, MULTI-PURPOSE DRY CHEMICAL
Fire Fighting Procedures:WEAR FULL PROTECTIVE CLOTHING & USE SCBA.

Spill Release Procedures:WEAR PROTECTIVE EQUIPMENT. SMALL: COLLECT &
TRANSFER TO A WASTE CONTAINER FOR DISPOSAL. FOR LARGE/BULK
QUANTITIES, COLLECT BY CAREFULLY MOPPING/WIPING & PLACE IN A
LABELLED, SEALED CONTAINER FOR DISPO SAL. WASH AREA W/A SUITABLE
CLEANING SOLVENT.

Handling and Storage Precautions:USE STORAGE CONDITIONS THAT WILL
MINIMIZE POTENTIAL SPILLS. KEEP DRY & STORE BETWEEN 59-86F. DON'T
REFRIGERATE.

Respiratory Protection:WEAR SCBA.
Ventilation:NO SPECIAL VENTILATION REQUIREMENTS.
Protective Gloves:IMPERMEABLE/LATEX
Eye Protection:RECOMMENDED
Work Hygienic Practices:REMOVE/LAUNDER CONTAMINATED CLOTHING BEFORE
REUSE. WASH HANDS & OTHER AREAS THOROUGHLY AFTER HANDLING THIS
MATERIAL.
Supplemental Safety and Health
A SUITABLE SOLVENT, SUCH AS ISOPROPYL ALCOHOL, SHOULD BE USED FOR
CLEANING, UNLESS OTHER STANDARD OPERATING PROCEDURES SUPERCEDE
THESE RECOMMENDATIONS.

Solubility in Water:INSOLUBLE
Appearance and Odor:WHITE TO OFF WHITE EMOLIENT CREAM; ODORLESS

Stability Indicator/Materials to Avoid:YES
Stability Condition to Avoid:REFRIGERATION
Hazardous Decomposition Products:TOXIC & CORROSIVE GASES & HYDROGEN
FLUORIDE.

Waste Disposal Methods:UNUSED PRODUCT SHOULD BE DISPOSED OF AT AN
APPROVED FACILITY IAW/FEDERAL, STATE & LOCAL REGULATIONS.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.